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Amgen
PRINCIPAL

Principal Systems Engineer – Clinical Computation Platform

AmgenVisit website ·Posted 1 month ago

Location

TS, IN

Experience

17+ years

Required Skills

PythonDockerKubernetesDevOpsAgileScrum

About the Role

India - Hyderabad
JOB ID: R-243700 LOCATION: India - Hyderabad WORK LOCATION TYPE: On Site DATE POSTED: May. 05, 2026 CATEGORY: Clinical
ABOUT AMGEN


Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier,fullerand longer. We discover, develop,manufactureand deliver innovative medicines to help millions of patients. Amgen helpedestablishthe biotechnology industry more than 40 years ago andremainson thecutting-edgeof innovation, using technology and human genetic data to push beyondwhat’sknown today.


ABOUT THE ROLE


Role Description:


Theroleis responsible forthe design, integration, and management of complex systems that encompass both hardware and software componentsinto theorganization’scloudinfrastructure.This individualwillbe responsible forall activities related to handling and supportingtheBusiness and platforms including system administration, as well as incorporatingnew technologiesunder the challenge of a sophisticated and constantly evolving technology landscape.This role involves ensuring that all parts of a system work together seamlessly to meet the organization’s requirements.


Roles . Responsibilities:

  • • Collaborate with business partners and other software engineers to develop and deploy the latest, advanced technologies in support of product optimization

  • • Work closely with the delivery and platform teams to ensure that the applications are aligned with standard city planning approved architectural and development guidelines

  • • Support selected efforts to design, build, and develop rapidProof-of-Concept(POC) automated solutions and services. Quickly and iteratively prove or disprove the concepts being considered

  • • Develop and design systems architecture, ensuringthatit meets both current and future needs of the organization

  • • Integrate hardware and software components into a cohesive system that meets functional and performance requirements

  • • Perform system testing and validation to ensure all components function correctly and efficiently

  • • Optimizesystem performance and troubleshoot any issues that arise during system operation

  • • Create andmaintaincomprehensive documentation of systems design, configurations, and procedures

  • • Work closely with other engineers, IT staff, and project managers to ensure successful implementation of systems

  • • Monitor andmaintainsystems to ensure they continue tooperateeffectively and efficiently

  • • Implement automation tools and processes to improve the efficiency and reliability ofthe system

  • • Conducttrainingand workshopsfor business teamsto share bestpractices in the industry.
  • Basic Qualifications and Experience:

  • • Master’s / Bachelor’s degree with 13 - 17 years of experience in Computer Science,ITor related field

  • Functional Skills:

    Must-Have Skills:

  • • Experiencein cloud platformsincludingAWS

  • • Experience with container technologies like Docker and Kubernetes

  • • Hands-on experience with computerized systems including troubleshooting, reliability, and performance improvements

  • • Experience with translating business requirements to technical requirements and recommend solutions for automation

  • • Proficiencyin programming languagesincludingR, Python

  • • Experience andstrong knowledge ofPOSIT Tools and Services

  • • Strong understanding of software development methodologies, including Agile and Scrum

  • Good-to-Have Skills:

  • • Experience with DevOps tools and practices

  • • Strong understanding of systems engineering processes and methodologies

  • • Experience with systems integration and validation

  • • Knowledge of Clinical Development domain
  • Professional Certifications:

  • • Scaled Agile Framework (SAFe) for Teams (preferred)
  • Soft Skills:

  • • Excellent analytical and troubleshooting skills

  • • Strong verbal and written communication skills

  • • Ability to work effectively with global, virtual teams

  • • High degree of initiative and self-motivation

  • • Ability to manage multiple priorities successfully

  • • Team-oriented, with a focus on achieving team goals

  • • Strong presentation and public speaking skills
  • Shift Information:


    This position requires you to work a later shift and may beassigneda second or third shift schedule. Candidates must be willing and able to work during evening or night shifts, asrequiredbased on business requirements.


    EQUAL OPPORTUNITY STATEMENT


    Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

    HireIQ AI InsightsBeta

    Ideal Candidate

    A systems architect with 13–17 years building production cloud infrastructure (AWS-focused) who has shipped containerized applications at scale and can translate clinical/regulatory requirements into DevOps automation.

    Estimated Salary Range(medium confidence)

    22 L – ₹35 L per year

    Likely Interview Questions

    1. 1.Walk us through a complex hardware-software integration project you led at cloud scale—what bottlenecks emerged and how did you resolve them with containerization/orchestration?
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    About Amgen

    Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics.

    10,000+ employees

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